Gtex 革新的GX技術創出事業 多様な微生物機能の開拓のためのバイオものづくりDBTL技術の開発

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関連論文

  • Tokunou, Y., Yamazaki, T., Okamoto, A. Decoding In-Cell Respiratory Enzyme Dynamics by Label-Free In-situ Electrochemistry. Proc. Natl. Acad. Sci. USA. 2025, 122, e2418926122 https://doi.org/10.1073/pnas.2418926122
  • Kosaka Y, Miyawaki Y, Mori M, Aburaya S, Nishizawa C, Chujo T, Niwa T, Miyazaki T, Sugita T, Fukuyama M, Taguchi H, Tomizawa K, Sugase K, Ueda M, Aoki W. Autonomous ribosome biogenesis in vitro. Nature Commun. 2025, 16(1), 514. doi: 10.1038/s41467-025-55853-7.
  • Tominaga M, Shima Y, Nozaki K, Ito Y, Someda M, Shoya Y, Hashii N, Obata C, Matsumoto-Kitano M, Suematsu K, Matsukawa T, Hosoya K, Hashiba N, Kondo A, Ishii J. Designing strong inducible synthetic promoters in yeasts. Nat. Commun. 2024, 15(1):10653. doi: 10.1038/s41467-024-54865-z.
  • Ciemniecki, J. A., Ho, C. L., Horak, R. D., Okamoto, A. Newman, D.K. Mechanistic study of a low-power bacterial maintenance state using high-throughput electrochemistry. Cell 2024, 187(24), 6882-6895. doi: 10.1016/j.cell.2024.09.042.
  • Tokunou, Y., Yamazaki, T., Okamoto, A. Decoding In-Cell Respiratory Enzyme Dynamics by Label-Free In-situ Electrochemistry. 2024 – researchsquare.com
    https://doi.org/10.21203/rs.3.rs-4306846/v1
  • Yoshimoto, S.; Aoki, S.; Ishikawa, M.; Suzuki, A.; Hori, K. Size‑dependent ability of AtaA to immobilize cells in Acinetobacter sp. Tol 5. Sci. Rep. 2024, 14:21039. https://doi.org/10.1038/s41598-024-71920-3
  • Takafuji, Y.; Fischer, T.; Miyazaki, K.; Honda, K. Complete Genome Sequences of Thermus thermophilus strains isolated from Shirahama Hot Spring in Japan. Microbiol. Resour. Announc. 2024, e00316-24.
    https://doi.org/10.1128/mra.00316-24
  • Fukawa, E.; Suzuki, Y.; Adachi, T.; Miyata, T.; Makino, F.; Tanaka, H.; Namba, K.; Sowa, K.; Kitazumi, Y.; Shirai, O. Structural and electrochemical elucidation of biocatalytic mechanisms in direct electron transfer-type D-fructose dehydrogenase. Electrochimica Acta 2024, 490, 144271. https://www.sciencedirect.com/science/article/pii/S0013468624005139
  • Toya, Y.; Shimizu, H. Coupling and uncoupling growth and product formation for producing chemicals. Curr. Opin. Biotechnol. 2024, 87, 103133.
    https://www.sciencedirect.com/science/article/pii/S0958166924000697
  • Ishii, J.; Tominaga, M.; Shima, Y.; Nozaki, K.; Ito, Y.; Someda, M.; Shoya, Y.; Hashii, N.; Obata, C.; Kitano, M. Designing strong inducible synthetic promoters in yeasts. 2024.        
    https://www.researchsquare.com/article/rs-4454036/latest
  • Yamada, R.; Yamamoto, C.; Sakaguchi, R.; Matsumoto, T.; Ogino, H. Development of a metabolic engineering technology to simultaneously suppress the expression of multiple genes in yeast and application in carotenoid production. World J. Microbiol. Biotechnol. 2024, 40 (7), 227.
    DOI:10.1007/s11274-024-04034-7.
  • Yamada, R.; Ando, K.; Sakaguchi, R.; Matsumoto, T.; Ogino, H. Induction of point and structural mutations in engineered yeast Saccharomyces cerevisiae improve carotenoid Production. World J. Microbiol. Biotechnol. 2024, 40 (7), 230.
    DOI:10.1007/s11274-024-04037-4.
  • Taniguchi, T.; Okahashi N.; Matsuda, F. 13C-metabolic flux analysis reveals metabolic rewiring in HL-60 neutrophil-like cells through differentiation and immune stimulation. Metab. Eng. Commun., 2024, 18, p. e00239.          
    DOI:10.1016/j.mec.2024.e00239.
  • Tanaka, K.; Bamba, T.; Kondo, A.; Hasunuma, T. Metabolomics-Based Development of bioproduction processes toward industrial-scale production. Curr. Opin. Biotechnol. 2024, 85, 103057.
    https://www.sciencedirect.com/science/article/pii/S0958166923001672